
A growth factor that speeds up healing for burns and wounds
Media release 14 September 2004
A Queensland PhD student’s discovery speeds up tissue growth and repair and
sparks off a new listed biotech company.
“The key to recovering from a burn or a wound is the
ability for cells to move and grow. We have discovered a naturally occurring
novel complex of growth factors that speeds this process up,” says Jennifer
Kricker, finalist in the Fresh Innovators forum and co-discoverer of the
complex, now called VitroGro.
“Speeding up healing reduces the risk of infection and
scarring,” says Jennifer. “Our team are also investigating the use of VitroGro
in treating diabetic and venous ulcers and tissue regeneration therapies for
bone, corneal and skin regrowth – in fact wherever cell movement and growth is
required.”
So far the studies in the lab have been promising. So
promising that a company has been set up and listed on the ASX to commercialise
the technology - Tissue Therapies Limited. And Jennifer, in her fourth and final
year of her PhD is a seed shareholder.
The work came out of Jennifer's investigations into a
particular growth factor - IGF-I - and how it interacted with proteins present
in the circulation and in tissues. In particular, she found that when IGF-I is
bound to two other proteins, that together, they were able to make skin cells
grow and migrate.
Her work was published in the scientific journal
Endocrinology.
"We need more young innovators like Jenny Kricker to
create the highly committed and expert human resources that are critical to the
success of Australian technology companies," says Greg Baynton, Managing
Director of Orbit
Capital, and Executive Director of Tissue Therapies. Orbit Capital is a
Brisbane-based boutique investment bank that has provided early financial
backing and corporate advice to Jennifer and Tissue Therapies.
“Ultimately we
would like to see a plaster available on the supermarket that is bioactive, that
is, a plaster that actively assists in wound repair,” says Dr Zee Upton, senior
lecturer at the Queensland University of Technology and co-inventor. “In the
interim we’re aiming for a dressing that can be used by clinicians when treating
wounds."
"Reducing the
healing time for wounds would not only benefit the patient, but also the
Australian health care budget,” says Dr Upton.
Jennifer’s
innovative work recently won her a place at Fresh Innovators – a national
initiative to bring the work of 16 early career innovators to public attention.
The sixteen are now talking to the media, schools and business about their
ideas. One of the 16 will win a study tour to the UK courtesy of the British
Council Australia.
VitroGro is a
registered trademark.
About the inventor:
Jennifer studied Science at Queensland
University of Technology and continued on to do honours at QUT in crayfish
digestive enzymes. She is currently completing her PhD.
For interview or more information:
Jennifer Kricker 07 3864 5177 mobile: 0404 060 030
Greg Baynton
0414 970 566
Images:
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VitroGro coating kit available from Tissue Therapies. Photo credit to
Tissue Therapies |
Jennifer preparing an experiment using VitroGro in a tissue culture
biohazard hood. |
VitroGro encourages cells to
move thereby speeding up the healing process |
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